Evaluation of continuous constant current and continuous pulsed current in sweat induction for cystic fibrosis diagnosis

Table 2 Comparison of number of exams with insufficient sweat weight (below 75 mg) between continuous constant current and sinusoidal and triangular continuous pulsed current

		Continuous constant current
	Sweat weight	Sufficient	Insufficient	p-value
Sinusoidal pulsed current	Sufficient	49 (89.1%)	3 (5.5%)	0.655^a
Sinusoidal pulsed current	Insufficient	2 (3.6%)	1 (1.8%)	0.655^a
Triangular pulsed current	Sufficient	172 (83.9%)	9 (4.4%)	0.523^b
Triangular pulsed current	Insufficient	13 (6.3%)	11 (5.4%)	0.523^b
Continuous pulsed current	Sufficient	221 (85%)	12 (4.6%)	0.333^c
Continuous pulsed current	Insufficient	15 (5.8%)	12 (4.6%)	0.333^c

Statistical analysis conducted through McNemar’s tests. Alpha = 0.05
^aNumber of observed agreements = 50 (90.91%); Number of agreements expected by chance = 48.4 (88.07%); Kappa = 0.238; SE of kappa = 0.232; 95% confidence interval (95%CI) = − 0.217 to 0.693; strength of agreement = fair
^bNumber of observed agreements = 183 (93.85%); number of agreements expected by chance = 163.9 (84.04%); Kappa = 0.614; SE of kappa = 0.101; 95%CI = 0.416 to 0.813; strength of agreement = good
^cNumber of observed agreements = 233 (89.62%); number of agreements expected by chance = 214 (82.3%); Kappa = 0.413; SE of kappa = 0.093; 95%CI = 0.232 to 0.595; strength of agreement = moderate. As shown in the table, the minor prevalence of insufficient sweat weight occurred for sinusoidal pulsed current (1.8%)

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