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Table 3 Comparison of sweat test result between continuous constant current and sinusoidal and triangular continuous pulsed current

From: Evaluation of continuous constant current and continuous pulsed current in sweat induction for cystic fibrosis diagnosis

Sweat test result

Continuous constant current

Cystic fibrosis

Borderline

Normal

p-value

Sinusoidal pulsed current

Cystic fibrosis

4

1

0

0.008 a

Borderline

0

16

1

Normal

1

11

15

Triangular pulsed current

Cystic fibrosis

14

5

0

0.423b

Borderline

6

49

12

Normal

0

16

62

Continuous pulsed current

Cystic fibrosis

18

6

0

0.033 c

Borderline

6

65

13

Normal

1

27

77

  1. Statistical analysis conducted through Wilcoxon signed-rank test (ordinal data). Alpha = 0.05
  2. aNumber of observed agreements = 35 (71.43%); number of agreements expected by chance = 19 (38.86%); Kappa = 0.533; SE of kappa = 0.101; 95% confidence interval (95%CI) = 0.335 to 0.73; strength of agreement = moderate; weighted Kappa = 0.563; strength of agreement = moderate
  3. bNumber of observed agreements = 125 (76.22%); number of agreements expected by chance = 66.1 (40.31%); Kappa = 0.602; SE of kappa = 0.056; 95%CI = 0.492 to 0.711; strength of agreement = good; weighted Kappa = 0.664; strength of agreement = good
  4. cNumber of observed agreements = 160 (75.12%); number of agreements expected by chance = 85.8 (40.3%); Kappa = 0.583; SE of kappa = 0.05; 95%CI = 0.485 to 0.681; strength of agreement = moderate; weighted Kappa = 0.639; strength of agreement = good. Statistically significant data are in bold. Additional analysis is shown as Fig. 7