Fig. 3

Boxplot of particle deposition for the three groups. Particle deposition fraction, DF, in the peripheral lungs for the three groups, measured for 50 nm particles and from 1300 mL volumetric sample depth (left panel), 50 nm particles and 1800 mL sample depth (middle panel) and 100 nm particles and 1800 mL sample depth (right panel). The red line indicates the median, the box 25th and 75th percentiles and the whiskers minimum and maximum values (two outliers displayed as a red marks). The p-values (Mann-Witney asymptotic significance, 2-tailed) are given in the figure. Significant differences between the groups are indicated with *. The 5% significance level for rejecting the null hypothesis is adjusted to 0.016 (Bonferroni correction)