From: Altered deposition of inhaled nanoparticles in subjects with chronic obstructive pulmonary disease
 | Healthy Never-Smokers (n = 17) | Asymptomatic Smokers (n = 15) | COPD (n = 16) |
---|---|---|---|
Male/Female | 9/8 | 6/9 | 7/9 |
Age [y] | 64 ± 6 | 62 ± 3 | 67 ± 7 |
Weight [kg] | 76 ± 14 | 76 ± 12 | 72 ± 13 |
Height [cm] | 173 ± 9 | 169 ± 9 | 170 ± 9 |
FEV1%pred | 110 ± 15 | 109 ± 13 | 61 ± 23*** |
VC %pred | 109 ± 20 | 112 ± 13 | 107 ± 18 |
FEV1/VC %pred | 78.6 ± 4.0 | 78.4 ± 5.6 | 44.9 ± 14.2*** |
DL,CO %pred | 92.0 ± 10 | 88.2 ± 13 | 60.2 ± 22***†|
GOLD-stage (1/2/3/4) | Â | Â | 3/7/5/1 |