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Fig. 6 | BMC Pulmonary Medicine

Fig. 6

From: Inhibition of Shp2 ameliorates monocrotaline-induced pulmonary arterial hypertension in rats

Fig. 6

Inhibition of Shp2 inhibits PDGF-stimulated activations of Akt and Stat3 pathways. a Representative images of blotting for p-Shp2/Shp2, p-Akt/Akt and p-Stat3/Stat3 in PASMCs. Quantifications of p-Shp2 (b), the ratio of pShp2/Shp2 (c), p-Akt (d), the ratio of p-Akt /Akt (e), p-Stat3 (f) and the ratio of p-Stat3 /Stat3 (g) (n = 3). Data was presented as means ± standard deviation (SD), n = 3, *P < 0.05, ** P < 0.01 and *** P < 0.001

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