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Fig. 6 | BMC Pulmonary Medicine

Fig. 6

From: Intratracheal administration of adipose derived mesenchymal stem cells alleviates chronic asthma in a mouse model

Fig. 6

Applying mASCs improved the inflammation in OVA-induced asthma model mice. a The expression of serum IL-1β, IL-4, IL-17F, and lgE in the PBS + PBS group, PBS + mASCs group, OVA + PBS group, and OVA+ mASCs group, respectively, by CHIP and ELISA; b The expression of IL-4, IL-17F, and IL-10 in BALF in the PBS + PBS group, PBS + mASCs group, OVA + PBS group, and OVA+ mASCs group, respectively, by CHIP; c The mRNA levels of IL-10, Foxp3, IL-17, and RORγ in the lung tissues of PBS + PBS group, PBS + mASCs group, OVA + PBS group, and OVA+ mASCs group, respectively, by qRT-PCR. *P < 0.05, **P < 0.01 and ***P < 0.001. mASCs, mouse adipose-derived mesenchymal stem cells; PBS, phosphate buffered saline; OVA, ovalbumin; BALF, bronchoalveolar lavage fluid

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