Impact of multidrug-resistant bacteria on outcome in patients with prolonged weaning

BMC Pulmonary Medicine

Table 2 Differences between patients with and without multidrug resistant (MDR) bacteria with prolonged weaning during stay in the weaning unit

Variable	Patients with MDR bacteria (n = 107)	Patients without MDR bacteria (n = 323)	p-value
p_aO₂ at weaning unit admission, mmHg	87.7 ± 42.2	88.6 ± 27.8	0.83
p_aCO₂ at weaning unit admission, mmHg	42.6 ± 9.6	39.6 ± 8.5	< 0.001
pH at weaning unit admission	7.44 ± 0.06	7.44 ± 0.06	0.29
Lactate at weaning unit admission, mmol/L	0.9 ± 0.41	0.9 ± 0.42	0.87
Secondary respiratory infection in the weaning unit^a, n (%)	40 (37.4)	142 (43.9)	0.28
Days of MV in the weaning unit	15.4 ± 15.8	16.9 ± 22.8	0.31
Weaning unit LOS, days	24.2 ± 26.8	22.9 ± 19.8	0.21
SAPS II at weaning unit discharge	28.3 ± 12.3	29.9 ± 11.5	0.24
Weaning category at discharge^b			0.05
3a	65 (60.7)	229 (72.0)
3b	9 (8.4)	13 (4.1)
3c	33 (30.9)	76 (23.2)

Data are given as mean ± standard deviation or number of patients (%)
MV Mechanical ventilation; p_aCO₂ Arterial carbon dioxide pressure; p_aO₂ Arterial oxygen pressure; SAPS II Simplified Acute Physiology Score II
Weaning categories were based on the German guidelines for prolonged weaning [10]
^aDefined as ventilator-associated pneumonia, ventilator-associated tracheobronchitis, pneumonic septic shock
^bCalculated for n = 318, weaning category not defined in 5 data sets of patients without MDR bacteria

ISSN: 1471-2466