Solid part size is an important predictor of nodal metastasis in lung cancer with a subsolid tumor

BMC Pulmonary Medicine

Table 1 Clinical, radiologic and pathologic characteristics of patients

Characteristic	Total (n = 269)
Age, years	62.4 ± 10.4
Male sex	115 (42.8)
Former/Current smoker	90 (33.5)
Previous extra-thoracic malignancy	34 (12.6)
Previous lung cancer	6 (2.2)
Tumor centrality	14 (5.2)
Radiologic N stage
N0	227 (84.4)
N1–2	42 (15.6)
T categories for subsolid tumor^a
cTis	23 (8.6)
cT1	203 (75.5)
cT2	43 (16.0)
EBUS	99 (36.8)
Operation extent
Segmentectomy	41 (15.2)
Lobectomy	228 (84.8)
Pathology
AAH/AIS	2 (0.7)
MIA	29 (10.8)
Invasive ADC	235 (87.4)
Invasive mucinous ADC	3 (1.1)
Pathologic N stage^b
N0	259 (96.3)
N1	5 (1.9)
N2	5 (1.9)

Data are presented as n (%) or mean ± standard deviation
AAH atypical adenomatous hyperplasia, ADC adenocarcinoma, AIS adenocarcinoma in situ, EBUS endobronchial ultrasound, MIA minimally invasive adenocarcinoma
^aT categories were classified by the total tumor size (cm) and solid part size (cm). Total tumor size was defined as a size including ground glass around the solid part; cTis (total tumor size of 0.6–3.0 cm with no solid part), cT1 (total tumor size of 0.6–3.0 cm with solid part size 0.6–3.0 cm) and cT2 (total tumor size of 3.0–7.0 cm with any solid part size)
^bPathologic N stage was determined by the final pathologic report after surgery

ISSN: 1471-2466