Table 1 Overrepresented pathways in SAECs based on KEGG analysis
From: Regional heterogeneity in response of airway epithelial cells to cigarette smoke
Pathway | p | Genes |
|---|---|---|
Rheumatoid arthritis | < 0.001 | CCL20, MMP1, IL1B, TLR2, FOS, IL8 |
TNF-signaling pathway | 0.001 | CCL20, PTGS2, IL1B, MAP3K8, FOS, TRAF1 |
Toll-like receptor-signaling pathway | 0.001 | SPP1, IL1B, MAP3K8, TLR2, FOS, IL8 |
Leishmaniasis | 0.001 | NCF1, PTGS2, IL1B, TLR2, FOS |
Malaria | 0.004 | CSF3, IL1B, TLR2, IL8 |
Amoebiasis | 0.005 | IL1B, IL1R2, TLR2, IL8, SERPINB2 |
NF-κB-signaling pathway | 0.020 | PTGS2, IL1B, TRAF1, IL8 |
MAPK-signaling pathway | 0.026 | NR4A1, PLA2G4A, IL1B, IL1R2, MAP3K8, FOS |
Chagas disease (American trypanosomiasis) | 0.032 | IL1B, TLR2, FOS, IL8 |