Fig. 7
From: Role of TLR4-p38 MAPK-Hsp27 signal pathway in LPS-induced pulmonary epithelial hyperpermeability
In vivo study of effect of p38 MAPK in LPS-induced ALI. C57 mice were pretreated with SB203580 before LPS (15 mg/kg) injection. (a) BALF/blood fluorescence intensity ratio and (b) Wet-to-dry lung weight ratio were measured; (c) protein concentration and (d) neutrophil cell counts in BALF were obtained; n = 3~ 4, *P < 0.05 versus control. (e) Lung Hematoxylin and eosin staining were obtained and lung injury score was calculated. n = 5, *P < 0.05