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Table 3 Demographic characteristics of the patients from the UHH and RBH cohort included in the survival analysis. Seven patients with DLco< 30 were excluded from the initial UHH cohort

From: Pirfenidone improves survival in IPF: results from a real-life study

Patients data UHH (n = 75) RBH (n = 136) P value
Age 72.5 ± 7.6a 62.5 ± 9.9a P < 0.0001
Gender (male/female) 64/11 96/40 P < 0.01
Smoking status
 Never smokers 26 27 P = 0.08
 Smokers 49 109 P = 0.34
Radiological pattern (Definite UIP/Possible UIP) 41/34 56/55 P = 0.7
Biopsy proven UIP 9 25  
FEV1 87.4 ± 21.5a 78.9 ± 15.6a P < 0.0006
FVC 81.8 ± 17.8a 79.3 ± 18.0a P = 0.16
DLco 56.7 ± 16.0a 46 ± 12.4a P < 0.0001
  1. UIP usual interstitial pneumonia, FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, DLco diffusing capacity of the lung for carbon monoxide
  2. aThe values are expressed as mean ± SD