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Table 3 Demographic characteristics of the patients from the UHH and RBH cohort included in the survival analysis. Seven patients with DLco< 30 were excluded from the initial UHH cohort

From: Pirfenidone improves survival in IPF: results from a real-life study

Patients data

UHH (n = 75)

RBH (n = 136)

P value

Age

72.5 ± 7.6a

62.5 ± 9.9a

P < 0.0001

Gender (male/female)

64/11

96/40

P < 0.01

Smoking status

 Never smokers

26

27

P = 0.08

 Smokers

49

109

P = 0.34

Radiological pattern (Definite UIP/Possible UIP)

41/34

56/55

P = 0.7

Biopsy proven UIP

9

25

 

FEV1

87.4 ± 21.5a

78.9 ± 15.6a

P < 0.0006

FVC

81.8 ± 17.8a

79.3 ± 18.0a

P = 0.16

DLco

56.7 ± 16.0a

46 ± 12.4a

P < 0.0001

  1. UIP usual interstitial pneumonia, FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, DLco diffusing capacity of the lung for carbon monoxide
  2. aThe values are expressed as mean ± SD