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Table 4 Diagnostic performance of pleural fluid CRP based on the ROC analysis (n = 132)

From: The usefulness of pleural fluid presepsin, C-reactive protein, and procalcitonin in distinguishing different causes of pleural effusions

 

Optimal cut-off point (mg/dL)

Sensitivity (%)

Specificity (%)

+LR

−LR

PPV (%)

NPV (%)

AUC

Accuracy (%)

Emp vs. other

≥4.91

63.6

89.3

5.93

0.41

35.0

96.4

0.757

87.1

Emp and PE vs. other

≥2.59

70.4

85.7

4.92

0.35

55.9

91.8

0.834

82.6

Emp, PE and TB vs. other

≥2.59

69.4

90.6

7.40

0.34

73.5

88.8

0.840

84.9

PE vs. other (excluding Emp)

≥2.18

81.3

81.0

4.27

0.23

39.4

96.6

0.859

81.0

Infectious vs. non-infectious

≥2.59

65.8

90.4

6.87

0.38

73.5

86.7

0.820

83.3

  1. Emp empyema, PE parapneumonic effusions, TB tuberculosis, +LR positive likelihood ratio −LR negative likelihood ratio, PPV positive predictive value, NPV negative predictive value, AUC area under the curve