Fig. 4

Administration with rWISP1 Aggravates Lung Injury Following Hepatic IRI. WT mice in sham and IRI group undergoing ischemia for 60 min and reperfusion for 6 h were treated intraperitoneally with either sterile PBS or rWISP1 (1 μg/g) at the onset of reperfusion (n = 6 respectively). H&E staining (a), W/D weight ratio (b), EBA permeability analysis (c), total cell counts (d) and proteins (e) in BALF and MPO levels (f) of lung samples from WT mice in sham and IRI group were performed.^*p < 0.05 compared with sham group, ^#p < 0.05 compared with PBS group, data are expressed as mean ± s.e.m. for all samples