Table 4 Post-bronchodilator obstruction (post-BD FEV1/FVC-ratio < 70%) after inhalation of salbutamol 400 μg at the follow-up according to relevant characteristics at baseline
Baseline characteristics | Post-BD FEV1/FVC < 70% | P-val1 | |
|---|---|---|---|
No (n = 49) | Yes (n = 7) | ||
Spirometry, mean (SD) | |||
dFEV1, ml/year | 34.5 (3.3) | 42.5 (10.4) | 0.42 |
FVC, l | 4.2 (0.2) | 4.2 (0.4) | 0.62 |
FVC, % of predicted | 108 (2) | 106 (9) | 0.70 |
FEV1, l | 3.3 (0.1) | 2.7 (0.3) | 0.10 |
FEV1, % of predicted | 84 (2) | 70 (6) | < 0.01 |
FEV1/FVC% | 78 (1) | 66 (1) | < 0.01 |
DLCO, mmol/(min × kPa) | 9.6 (0.3) | 7.9 (0.9) | 0.10 |
DLCO, % of predicted | 100 (2) | 83 (7) | < 0.01 |
KCO, mmol/(min × kPa × l) | 1.7 (0.04) | 1.3 (0.1) | < 0.01 |
KCO, % of predicted | 120 (2) | 102 (10) | 0.01 |
Blood values | |||
Haemoglobin, g/dl | 15.0 (0.16) | 15.1 (0.6) | 0.79 |
WBCs, 109/l | 5.9 (0.20) | 7.7 (1.2) | < 0.01 |
Neutrophils, 109/l | 3.4 (0.7) | 4.7 (0.8) | 0.02 |
Eosinophils, 109/l | 0.1 (0.01) | 0.2 (0.04) | 0.38 |
Sputum cells | |||
Neutrophils, % | 62 (3) | 57 (7) | 0.54 |
Macrophages, % | 36 (3) | 37 (5) | 0.83 |
Eosinophils, % | 0.60 (0.1) | 3.7 (1.1) | < 0.01 |
Pack-years, mean (SD) | 9.2 (1.7) | 23.9 (1.4) | 0.01 |
Age, years, mean (SD) | 55.4 (1.3) | 63.1 (2.5) | 0.04 |
Sex, male, n (%) | 27 (87) | 4 (13) | 0.83 |