Table 1 Concordance within sib-pairs for PI and correlation between the pancreatic status and meconium ileus (MI), severity of lung disease, CF liver disease (CFLD), CF related diabetes (CFRD) and recurrent panreatitis (RP) in 101 pairs of siblings with CF. N: absence of the symptom/complication
From: Clinical expression of cystic fibrosis in a large cohort of Italian siblings
Concordance within sib-pairs for PI (%)95.1 | ||||
|---|---|---|---|---|
PI/PI | PI/PS | PS/PS | ||
Number of sib-pairs | 58 | 3 | 40 | |
Meconium ileus: | MI/MI | 4 | 0 | 0 |
MI/N | 5 | 0 | 2 | |
N/N | 49 | 3 | 38 | |
Lung disease: | Severe/severe | 6 | 0 | 0 |
Severe/mild | 15 | 1 | 5 | |
Mild/mild | 37 | 2 | 35 | |
CF liver disease: | CFLD/CFLD | 3 | 2 | 0 |
CFLD/N | 11 | 0 | 2 | |
N/N | 44 | 1 | 38 | |
CF related diabetes: | CFRD/CFRD | 5 | 0 | 1 |
CFRD/N | 11 | 3 | 2 | |
N/N | 42 | 0 | 37 | |
Pancreatitis: | RP/RP | 1 | 0 | 1 |
RP/N | 1 | 0 | 6 | |
N/N | 56 | 3 | 33 | |