Fig. 8From: Endothelial cells from pulmonary endarterectomy specimens possess a high angiogenic potential and express high levels of hepatocyte growth factorThe hypothesized etiology of insufficient angiogenesis in pulmonary endarterectomy specimens. Insufficient angiogenesis in the organized thrombi might consist of complex conflicts between anti-angiogenic factors (decreased mRNA expression of angiogenetic factor like KDR, loscal anti-angiogenic cytokines) and pro-angiogenic factors (plasma microparticles). The finding of pro-angiogenic factors in the thrombus vessels in the present study (endothelial cells with high angiogenic potential) may represent the latterBack to article page