Table 1 Basic characteristics of patients whose blood sample were collected for the analysis of serum HGF in Fig. 7a

Number of patients

61

12

Age (y)

62.1 ± 10.6

71.0 ± 12.4

<  0.01

Sex (M:F)

14:47

0:12

n.s.

Systolic blood pressure (mmHg)

121.9 ± 21.5

135.4 ± 10.8

< 0.05

Diastolic blood pressure (mmHg)

73.9 ± 14.3

71.2 ± 10.0

n.s.

Total cholesterol (mg/dl)

192.6 ± 33.8

197.5 ± 24.9

n.s.

ALT (U/l)

25.9 ± 10.2

24.5 ± 6.1

n.s

AST (U/l)

20.5 ± 11.7

19.9 ± 6.93

n.s.

ɤ-GTP (U/l)

48.6 ± 49.9

39.5 ± 49.8

n.s.

C-Reactive Protein (mg/dl)

0.18 ± 0.33

0.11 ± 0.16

n.s.

BNP (pg/ml)

147.2 ± 264.5

40.1 ± 34.4

n.s.

Disease duration (month)^a

32.1 ± 36.6

89.4 ± 42.6

<  0.01

Mean Pulmonary artery pressure (mmHg)

41.8 ± 10.3

–

–

Pulmonary artery resistance (dyne.sec.cm^− 5)

661.6 ± 287.7

–

–

Cardiac Index (L/min/m²)

2.74 ± 0.68

–

–

NYHA(I:II:III:IV)

0:42:18:1

–

–