Table 1 Schedule of Events (SOE)

Eligibility assessment

x

Xpert MTB/RIF (Ultra) assay

x

Sputum smear and culture

x

x

x

x

x

(x)

(x)

(x)

(x)

Drug sensitivity testing

x

Demographic data

x

Clinical examination

x

x

x

x

x

x

x

x

x

Chest X-ray

x

x

x

Lung function assessment

x

x

x

x

x

x

x

ECG

x

x

x

Medical history (update)

x

x

x

x

x

x

x

x

x

TB treatment and adherence

x

x

x

x

(x)

(x)

(x)

(x)

Quality of life/patient’s cost questionnaire

x

x

x

x

x

HIV test (CD4 count)

x

x

x

Hepatitis B serology

x

Haematology and Biochemistry

x

x

x

x

Urine dip stick test

x

x

x

x

Blood storage for nested research studies

x

x

x

x

x

x

x

Sputum storage for nested research studies

x

x

x

x

x

(x)

(x)

(x)

(x)

Urine storage for nested research studies

x

x

x

x

(x)

(x)

(x)

(x)