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Table 1 Clinical characteristics of the training and validation group

From: Development and validation of a simple-to-use clinical nomogram for predicting obstructive sleep apnea

Characteristics Training group (n = 2913)   Validation group (n = 1249)  
Demographics non-OSA (n = 537) OSA (n = 2376) P value non-OSA (n = 238) OSA (n = 1011) P value
Age, years 37(30~47) 42(34~53) < 0.001 37(30~47) 43(34~53) < 0.001
Male (%) 58.8 84.7 < 0.001 61.8 84.6 < 0.001
BMI, Kg/m2 23.71(21.79~25.52) 27.04(24.77~29.39) < 0.001 23.28(21.29~25.71) 26.45(24.45~29.06) < 0.001
NC, cm 36(34~39) 40(38~42) < 0.001 36.75(34~38) 40(38~42) < 0.001
WC, cm 86(80~92) 97(91~103) < 0.001 85 (79~92) 96 (90~103) < 0.001
HC, cm 96(92~100) 102(97~106) < 0.001 96(92~100) 101(97~106) < 0.001
Glucose (mmol/L) 5.01(4.65~5.31) 5.31(4.97~5.82) < 0.001 4.97(4.65~5.30) 5.28(4.94~5.77) < 0.001
Insulin (uU/ml) 7.35(5.23~10.49) 11.65(7.96~16.90) < 0.001 7.11(4.92~9.83) 10.18(6.75~15.78) < 0.001
SBP, mmHg 120(110~126) 125(117~135) < 0.001 120(111~126) 125(116~135) < 0.001
DBP, mmHg 77(70~81) 80(74~88) < 0.001 77(70~82) 80(73~87) < 0.001
TC 4.36(3.76~4.91) 4.75(4.20~5.35) < 0.001 4.30(3.75~4.95) 4.78(4.19~5.40) < 0.001
TG 1.10(0.75~1.58) 1.63(1.16~2.38) < 0.001 1.12(0.72~1.62) 1.62(1.12~2.35) < 0.001
HDL-C 1.10(0.96~1.285) 1.02(0.90~1.18) < 0.001 1.10(0.96~1.29) 1.03(0.90~1.18) < 0.001
LDL-C 2.63(2.14~3.14) 3.02(2.53~3.53) < 0.001 2.63(2.18~3.23) 3.02(2.50~3.59) < 0.001
ApoA-I 1.10(0.96~1.25) 1.05(0.95~1.19) < 0.001 1.07(0.96~1.22) 1.07(0.96~1.19) 0.409
ApoB 0.74(0.63~0.86) 0.84(0.74~0.96) < 0.001 0.72(0.63~0.87) 0.84(0.74~0.96) < 0.001
ApoE 3.89(3.22~4.69) 4.32(3.55~5.46) < 0.001 3.81(3.10~4.78) 4.34(3.58~5.38) < 0.001
Lpa 7.88(4.29~16.85) 7.4(3.8~15.18) 0.037 7.70(4.25~16.35) 7.7(3.8~15.3) 0.532
AHI 1.4(0.5~2.9) 40.9(18.7~62.1) < 0.001 1.85(0.60~3.40) 38.9(17.8~61.2) < 0.001
Mean SaO2 97(96~97) 94(92~95.8) < 0.001 97(96~97.45) 94(92~95.7) < 0.001
Minimum SaO2 94(91~96) 78(68~85) < 0.001 94(91~96) 79(68~85) < 0.001
ODI 1.6 (0.6~3.5) 41.2(18.13~63.5) < 0.001 1.8(0.7~3.5) 38.2(18.2~63) < 0.001
MAI 11.8(7.6~19.1) 25(13.2~43.78) < 0.001 12.8(8.05~20.43) 25.7(13.8~45.2) < 0.001
  1. The data are presented as means and standard deviation; skewed data are presented as the median (IQR), and categorical data as the number (percentage)
  2. Differences in the baseline characteristics among the two groups were examined using independent samples t test or Mann–Whitney U test for continuous variables and chi-square test or Fisher’s exact test for categorical variables
  3. OSA obstructive sleep apnea, BMI body mass index, NC neck circumference, WC waist circumference, HC hip circumference, SBP systolic blood pressure, DBP diastolic blood pressure, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein; cholesterol, ApoA-I apolipoprotein A-I, ApoB apolipoprotein B, AHI apnoea–hypopnea index, SaO2 oxygen saturation, ODI oxygen desaturation index, MAI micro-arousal index