|
Characteristics
|
Training group (n = 2913)
| |
Validation group (n = 1249)
| |
|---|
|
Demographics
|
non-OSA (n = 537)
|
OSA (n = 2376)
|
P value
|
non-OSA (n = 238)
|
OSA (n = 1011)
|
P value
|
|---|
|
Age, years
|
37(30~47)
|
42(34~53)
|
< 0.001
|
37(30~47)
|
43(34~53)
|
< 0.001
|
|
Male (%)
|
58.8
|
84.7
|
< 0.001
|
61.8
|
84.6
|
< 0.001
|
|
BMI, Kg/m2
|
23.71(21.79~25.52)
|
27.04(24.77~29.39)
|
< 0.001
|
23.28(21.29~25.71)
|
26.45(24.45~29.06)
|
< 0.001
|
|
NC, cm
|
36(34~39)
|
40(38~42)
|
< 0.001
|
36.75(34~38)
|
40(38~42)
|
< 0.001
|
|
WC, cm
|
86(80~92)
|
97(91~103)
|
< 0.001
|
85 (79~92)
|
96 (90~103)
|
< 0.001
|
|
HC, cm
|
96(92~100)
|
102(97~106)
|
< 0.001
|
96(92~100)
|
101(97~106)
|
< 0.001
|
|
Glucose (mmol/L)
|
5.01(4.65~5.31)
|
5.31(4.97~5.82)
|
< 0.001
|
4.97(4.65~5.30)
|
5.28(4.94~5.77)
|
< 0.001
|
|
Insulin (uU/ml)
|
7.35(5.23~10.49)
|
11.65(7.96~16.90)
|
< 0.001
|
7.11(4.92~9.83)
|
10.18(6.75~15.78)
|
< 0.001
|
|
SBP, mmHg
|
120(110~126)
|
125(117~135)
|
< 0.001
|
120(111~126)
|
125(116~135)
|
< 0.001
|
|
DBP, mmHg
|
77(70~81)
|
80(74~88)
|
< 0.001
|
77(70~82)
|
80(73~87)
|
< 0.001
|
|
TC
|
4.36(3.76~4.91)
|
4.75(4.20~5.35)
|
< 0.001
|
4.30(3.75~4.95)
|
4.78(4.19~5.40)
|
< 0.001
|
|
TG
|
1.10(0.75~1.58)
|
1.63(1.16~2.38)
|
< 0.001
|
1.12(0.72~1.62)
|
1.62(1.12~2.35)
|
< 0.001
|
|
HDL-C
|
1.10(0.96~1.285)
|
1.02(0.90~1.18)
|
< 0.001
|
1.10(0.96~1.29)
|
1.03(0.90~1.18)
|
< 0.001
|
|
LDL-C
|
2.63(2.14~3.14)
|
3.02(2.53~3.53)
|
< 0.001
|
2.63(2.18~3.23)
|
3.02(2.50~3.59)
|
< 0.001
|
|
ApoA-I
|
1.10(0.96~1.25)
|
1.05(0.95~1.19)
|
< 0.001
|
1.07(0.96~1.22)
|
1.07(0.96~1.19)
|
0.409
|
|
ApoB
|
0.74(0.63~0.86)
|
0.84(0.74~0.96)
|
< 0.001
|
0.72(0.63~0.87)
|
0.84(0.74~0.96)
|
< 0.001
|
|
ApoE
|
3.89(3.22~4.69)
|
4.32(3.55~5.46)
|
< 0.001
|
3.81(3.10~4.78)
|
4.34(3.58~5.38)
|
< 0.001
|
|
Lpa
|
7.88(4.29~16.85)
|
7.4(3.8~15.18)
|
0.037
|
7.70(4.25~16.35)
|
7.7(3.8~15.3)
|
0.532
|
|
AHI
|
1.4(0.5~2.9)
|
40.9(18.7~62.1)
|
< 0.001
|
1.85(0.60~3.40)
|
38.9(17.8~61.2)
|
< 0.001
|
|
Mean SaO2
|
97(96~97)
|
94(92~95.8)
|
< 0.001
|
97(96~97.45)
|
94(92~95.7)
|
< 0.001
|
|
Minimum SaO2
|
94(91~96)
|
78(68~85)
|
< 0.001
|
94(91~96)
|
79(68~85)
|
< 0.001
|
|
ODI
|
1.6 (0.6~3.5)
|
41.2(18.13~63.5)
|
< 0.001
|
1.8(0.7~3.5)
|
38.2(18.2~63)
|
< 0.001
|
|
MAI
|
11.8(7.6~19.1)
|
25(13.2~43.78)
|
< 0.001
|
12.8(8.05~20.43)
|
25.7(13.8~45.2)
|
< 0.001
|
- The data are presented as means and standard deviation; skewed data are presented as the median (IQR), and categorical data as the number (percentage)
- Differences in the baseline characteristics among the two groups were examined using independent samples t test or Mann–Whitney U test for continuous variables and chi-square test or Fisher’s exact test for categorical variables
- OSA obstructive sleep apnea, BMI body mass index, NC neck circumference, WC waist circumference, HC hip circumference, SBP systolic blood pressure, DBP diastolic blood pressure, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein; cholesterol, ApoA-I apolipoprotein A-I, ApoB apolipoprotein B, AHI apnoea–hypopnea index, SaO2 oxygen saturation, ODI oxygen desaturation index, MAI micro-arousal index
