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Fig. 2 | BMC Pulmonary Medicine

Fig. 2

From: TRAIL signals through the ubiquitin ligase MID1 to promote pulmonary fibrosis

Fig. 2

Serum from IPF patients had elevated levels of TRAIL (a) and lung biopsies elevated MID1 (b) protein, which corresponded with a trend towards decreased activity of PP2A (c) when compared to those from control subjects. The percentage predicted diffusing lung capacity for carbon monoxide (DLco) did not have a strong inverse association with serum TRAIL (d) but was inversely associated with MID1 protein (e) and correlated with the levels of PP2A activity (f) in lung biopsies from IPF patients. n = 8, * p < 0.05

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