Fig. 4From: CD147 increases mucus secretion induced by cigarette smoke in COPDExpression of MUC5AC and CD147 induced by CS extract in HBE cells. HBE cells were treated with various concentration of CS extract (from 5 to 15%) for 24 h. MUC5AC protein (a) and mRNA (b) levels were detected by ELISA and RT-PCR, respectively. CD147 protein (c) and mRNA (d) levels were assessed by Western blotting and RT-PCR, respectively. *p < 0.05, compared with 0% CS extract, **p < 0.05 vs. compared with 5% CS extract, ***p < 0.05, compared with 10% CS extract. The data are representative of 3 separate experimentsBack to article page