Oxygen desaturation during the 6-min walk test as a risk for osteoporosis in non-cystic fibrosis bronchiectasis

BMC Pulmonary Medicine

Table 3 Stepwise multivariate regression analysis of variables associated with BMD at femoral neck

	Full model					Stepwise
Parameter	beta	Standard error	95% CI.	t	p-value	beta	Standard error	95% CI	t	p-value
Gender	0.276	0.312	−0.351~ 0.903	0.884	0.381
Age (yr)	−0.034	0.013	−0.061 ~ − 0.008	−2.603	0.012	− 0.036	0.011	− 0.057 ~ − 0.015	−3.396	0.001
BMI (kg/m²)	0.065	0.026	0.012 ~ 0.117	2.462	0.017	0.060	0.022	0.016 ~ 0.105	2.711	0.009
Desaturation	−0.937	0.337	−1.615 ~ − 0.260	−2.778	0.008	−0.913	0.228	−1.37 ~ − 0.456	−3.999	< 0.001
HRCT score	0.035	0.032	−0.030 ~ 0.100	1.078	0.286
Lowest SpO₂ during 6MWT (%)	0.003	0.023	−0.043 ~ 0.050	0.146	0.885
6MWD (M)	0.001	0.001	−0.002 ~ 0.004	0.557	0.58
FEV₁(L)	−0.032	0.301	−0.636 ~ 0.572	− 0.107	0.916
Severe exacerbation	−0.059	0.06	−0.180 ~ 0.062	− 0.975	0.334	−0.078	0.028	−0.134 ~ − 0.022	−2.807	0.007
Short-term systemic corticosteroid loading	−0.01	0.035	−0.081~ 0.060	− 0.291	0.772

Abbreviations: HRCT high resolution computed tomography, BMI body mass index, 6MWT six minute walk test, SpO₂ oxygen saturation by pulse oximetry, 6MWD six minute walk distance, FEV₁ forced expiratory volume in 1 s, CI confidence interval

ISSN: 1471-2466