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Fig. 6 | BMC Pulmonary Medicine

Fig. 6

From: Ligustrazin increases lung cell autophagy and ameliorates paraquat-induced pulmonary fibrosis by inhibiting PI3K/Akt/mTOR and hedgehog signalling via increasing miR-193a expression

Fig. 6

Effect of ligustrazin on Smo, SHH, and Gli1 mRNA and protein levels in murine lung tissues. Mice were treated with ligustrazin and PQ for 14 d. The relative levels of Gli-1, SHH, and Smo mRNA and protein expression levels were measured with qRT-PCR and western blotting, respectively. a Relative levels of Gli-1, SHH, and Smo mRNA. b-c Representative western blot results for Smo, SHH, and Gli-1 protein levels. All expression data were normalized to β-actin. Bars indicate the mean ± SD (n = 3). **p < 0.01, *p < 0.05 vs. controls

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BMC Pulmonary Medicine

ISSN: 1471-2466

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