Table 2 Percentages of lymphocyte subsets in bronchoalveolar lavage fluid of patients with diffuse lung diseases (DLD)
From: NK and NKT cells in the diagnosis of diffuse lung diseases presenting with a lymphocytic alveolitis
Median percentage (P25-P75) | All patients (n = 202) | Sarcoidosis (n = 106) | Hypersensitivity pneumonitis (n = 53) | Other DLDs | |||
|---|---|---|---|---|---|---|---|
All (n = 43) | Organising pneumonia (n = 10) | Pulmonary involvement in connective tissue diseases (n = 25) | Idiopathic pulmonary fibrosis (n = 8) | ||||
T lymphocytes* | 92.5 (87.5–95.9) | 94.1 (90.0–96.4) | 88.1 (83.0–92.9) | 93.5 (87.2–96.6) | 93.1 (86.0–95.4) | 93.7 (88.8–96.7) | 93.7 (87.4–96.9) |
CD4+ T cells* | 69.5 (46.8–82.3) | 77.8 (67.5–84.7) | 54.0 (36.0–73.8) | 51.6 (29.3–71.9) | 45.7 (30.7–68.8) | 55.0 (38.3–72.1) | 37.1 (25.0–80.2) |
CD8+ T cells* | 24.9 (13.2–48.4) | 18.1 (11.9–28.6) | 39.1 (21.2–57.8) | 46.8 (24.8–65.7) | 50.4 (24.9–64.8) | 40.8 (24.2–58.3) | 56.8 (18.2–72.7) |
CD4/CD8 ratio* | 2.8 (1.0–6.3) | 4.3 (2.4–7.1) | 1.4 (0.6–3.5) | 1.1 (0.5–2.9) | 0.9 (0.5–2.8) | 1.4 (0.7–3.0) | 0.7 (0.3–5.2) |
NK cells* | 1.5 (0.8–2.6) | 1.3 (0.6–2.1) | 2.3 (1.4–6.5) | 1.0 (0.5–2.0) | 0.9 (0.3–1.3) | 1.1 (0.6–2.1) | 1.2 (0.7–4.1) |
NKT cells† | 2.9 (1.3–6.4) | 2.8 (1.4–5.6) | 3.8 (1.7–8.2) | 2.7 (1.1–6.4) | 2.9 (1.2–8.5) | 2.6 (1.0–6.5) | 2.2 (0.8–5.3) |
B lymphocytes** | 0.3 (0.1–0.8) | 0.3 (0.1–0.7) | 0.6 (0.2–1.1) | 0.4 (0.1–1.1) | 0.4 (0.2–0.8) | 1.0 (0.2–1.6) | 0.2 (0.1–0.5) |