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Table 3 Uni- and multi-variate logistic regression analyses assessing the association between atopy or atopic disease and tuberculosis status

From: Asthma and atopy prevalence are not reduced among former tuberculosis patients compared with controls in Lima, Peru

Signs/symptoms of atopy

Tuberculosisa

Odds ratio (95% CI)

p-value

Atopyb

 Univariatec

0.57 (0.37, 0.88)

0.01

 Multivariated

0.64 (0.41, 1.01)

0.054

Allergic rhinitise

 Univariatec

0.64 (0.41, 1.02)

0.06

 Multivariated

0.76 (0.47, 1.24)

0.28

Asthmaf

 Univariatec

0.96 (0.59, 1.57)

0.87

 Multivariated

1.18 (0.69, 2.00)

0.55

Elevated FeNOg

 Univariatec

1.50 (0.94, 2.40)

0.09

 Multivariated

1.30 (0.78, 2.17)

0.32

Any atopic diseaseh

 Univariatec

0.70 (0.46, 1.08)

0.11

 Multivariated

0.86 (0.54, 1.36)

0.52

  1. CI -confidence interval, FeNO – fraction of exhaled nitric oxide
  2. aIncluded patients successfully treated for drug susceptible and drug-resistant disease; the cohort without tuberculosis (community controls) served as the reference group;
  3. bA positive skin prick test (> 3 mm greater than the negative control) to any one of the following allergens; house dust mite (D. farinae, D. pteronyssinus, B. tropicalis), cockroach (B. germanica, P. americana), cat dander, dog dander, grasses (ryegrass, grass mix), or mould (A. fumigatus, A. alternata);
  4. cUnadjusted univariate analyses;
  5. dMultivariate analysis adjusted for crowding index, gender and age in accordance with the DAG in (Fig. 1);
  6. eSymptoms of allergic rhinitis (hayfever) or prior medical diagnosis;
  7. fAsthma symptoms of wheeze in the last 12 months or diagnosed asthma or a positive bronchodilator response recorded on spirometry;
  8. gElevated FeNO > 50 ppb (parts per billion) for adults or > 35 ppb for children (under 18 years); marker of airway inflammation;
  9. hEither allergic rhinitis (e) or Asthma (f)