Signs/symptoms of atopy | Tuberculosisa |
---|
Odds ratio (95% CI) | p-value |
---|
Atopyb |
 Univariatec | 0.57 (0.37, 0.88) | 0.01 |
 Multivariated | 0.64 (0.41, 1.01) | 0.054 |
Allergic rhinitise |
 Univariatec | 0.64 (0.41, 1.02) | 0.06 |
 Multivariated | 0.76 (0.47, 1.24) | 0.28 |
Asthmaf |
 Univariatec | 0.96 (0.59, 1.57) | 0.87 |
 Multivariated | 1.18 (0.69, 2.00) | 0.55 |
Elevated FeNOg |
 Univariatec | 1.50 (0.94, 2.40) | 0.09 |
 Multivariated | 1.30 (0.78, 2.17) | 0.32 |
Any atopic diseaseh |
 Univariatec | 0.70 (0.46, 1.08) | 0.11 |
 Multivariated | 0.86 (0.54, 1.36) | 0.52 |
- CI -confidence interval, FeNO – fraction of exhaled nitric oxide
- aIncluded patients successfully treated for drug susceptible and drug-resistant disease; the cohort without tuberculosis (community controls) served as the reference group;
- bA positive skin prick test (> 3 mm greater than the negative control) to any one of the following allergens; house dust mite (D. farinae, D. pteronyssinus, B. tropicalis), cockroach (B. germanica, P. americana), cat dander, dog dander, grasses (ryegrass, grass mix), or mould (A. fumigatus, A. alternata);
- cUnadjusted univariate analyses;
- dMultivariate analysis adjusted for crowding index, gender and age in accordance with the DAG in (Fig. 1);
- eSymptoms of allergic rhinitis (hayfever) or prior medical diagnosis;
- fAsthma symptoms of wheeze in the last 12 months or diagnosed asthma or a positive bronchodilator response recorded on spirometry;
- gElevated FeNO > 50 ppb (parts per billion) for adults or > 35 ppb for children (under 18 years); marker of airway inflammation;
- hEither allergic rhinitis (e) or Asthma (f)