Table 1 Characteristics of never- and ever-smokers included in the current study
| Â | Never-smokers | Ever-smokers | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
LifeLines | Vla-Vlab | RS I | RS II | RS III | LifeLines | Vla-Vlab | RS I | RS II | RS III | |
N with no missing data | 5070 | 432 | 408 | 379 | 747 | 4855 | 823 | 640 | 583 | 1088 |
Males, N (%) | 1942 (38) | 103 (23) | 81 (20) | 124 (33) | 308 (41) | 2312 (48) | 590 (72) | 375 (59) | 343 (59) | 531 (49) |
Age (yrs), median (min-max) | 46 (18–89) | 54 (36–79) | 78 (72–94) | 71 (65–98) | 62 (51–93) | 49 (22–85) | 53 (35–79) | 79 (72–95) | 71 (65–93) | 62 (52–93) |
Height (cm), mean (SD) | 174 (9) | 166 (9) | 163 (9) | 166 (9) | 171 (9) | 175 (9) | 173 (8) | 168 (9) | 171 (9) | 172 (9) |
Current-smokers, N (%) | – | – | – | – | – | 2171 (45) | 478 (58) | 99 (16) | 108 (19) | 298 (27) |
Pack-years (yrs), mean (SD) | – | – | – | – | – | 17 (11) | 27 (21) | 29 (21) | 29 (21) | 27 (20) |
Pulmonary function, mean (SD) | ||||||||||
 FEV1%predicted (%), mean (SD)a | 98 (13) | 91 (13) | 101 (18) | 102 (16) | 101 (16) | 94 (14) | 85 (15) | 98 (23) | 96 (21) | 99 (19) |
 FEV1/FVC (%), mean (SD)b | 78 (7) | 76 (7) | 77 (7) | 79 (6) | 78 (6) | 75 (8) | 72 (10) | 74 (9) | 74 (9) | 75 (8) |
 FEV1/FVC <70%, N (%) | 548 (11) | 77 (18) | 51 (13) | 27 (7) | 75 (10) | 1107 (23) | 287 (35) | 163 (26) | 151 (26) | 235 (22) |
 FEV1/FVC < LLN, N (%) | 401 (8) | 49 (11) | 9 (2) | 9 (2) | 25 (3) | 833 (17) | 212 (26) | 63 (10) | 62 (11) | 122 (11) |
 Both FEV1/FVC <70% and < LLN, N (%) | 371 (7) | 49 (11) | 9 (2) | 9 (2) | 25 (3) | 802 (17) | 207 (25) | 63 (10) | 62 (11) | 122 (11) |
Moderate/severe COPD, N (%)c | 106 (2) | 26 (6) | 21 (5) | 9 (2) | 16 (2) | 310 (6) | 145 (18) | 90 (14) | 90 (15) | 104 (10) |