Table 1 Main clinical characteristics of the patients
From: Clinical significance of long non-coding RNA HOTTIP in early-stage non-small-cell lung cancer
Characteristics | Value | N = 99 N (%) |
|---|---|---|
Sex | Male | 77 (77.8) |
Female | 22 (22.2) | |
Age, yrs. | Mean (Range) | 66 (32–84) |
<=65 | 49 (49.5) | |
> 65 | 50 (50.5) | |
ECOG PSa | 0 | 20 (20.2) |
1 | 79 (79.8) | |
Stage | I | 73 (73.7) |
II | 26 (26.3) | |
T | 1 | 47 (47.5) |
2 | 49 (49.5) | |
3 | 3 (3) | |
N | 0 | 88 (88.9) |
1 | 11 (11.1) | |
Histology | Adenocarcinoma | 55 (55.5) |
Squamous cell carcinoma | 36 (36.4) | |
Others | 8 (8.1) | |
Type of surgery | Lobectomy/bilobectomy | 89 (89.9) |
Pneumonectomy | 4 (4) | |
Atypical Resectionb | 6 (6.1) | |
Smoking history | Current Smoker | 34 (34.4) |
Former Smoker | 53 (53.5) | |
Never smoker | 12 (12.1) | |
Adjuvant chemotherapy | Yes | 23 (23.2) |
No | 76 (76.8) | |
Relapse | No | 68 (68.7) |
Yes | 31 (31.3) | |
Emphysema | Yes | 48 (48.5) |
No | 44 (44.4) | |
Unknown | 7 (7.1) | |
COPDc | Yes | 64 (64.6) |
No | 35 (35.4) | |
DLCOd (%) | Mean (Range) | 73.4 (35–101) |
Molecular features | TP53 mutations | 31/94 (33) |
KRAS mutations | 20/98 (20.4) | |
EGFR mutationse | 14/47 (29.8) |