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Fig. 3 | BMC Pulmonary Medicine

Fig. 3

From: Reduced transient receptor potential vanilloid 2 expression in alveolar macrophages causes COPD in mice through impaired phagocytic activity

Fig. 3

Effects of 10% CSE and TRPV2 knockdown on phagocytosis function. a MH-S cells were stimulated with either vehicle or 10% CSE for indicated times, and then exposed to FITC-dextran for 6 h before harvesting for measurement of luminescence intensity. The data represent mean + standard error (n = 4–6) of fold change of luminescence intensity with (w) FITC-dextran vs. without (wt) FITC-dextran. *p < 0.05. b MH-S cells transfected with either GFP siRNA (control) or TRPV2 siRNA were cultured with FITC-dextran before harvesting for measuring luminescence intensity. The data represent mean + standard error (n = 4–6 per group) of fold change of luminescence intensity with (w) FITC-dextran vs. without (wt) FITC-dextran. **p < 0.01

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