| Enrollment (month) | Scheduled visits for subjects (month) | |||
---|---|---|---|---|---|
 | 0 | 6, 12, 18, 24, 30 | 36 | 42, 48, 54, 60, 66 | 72 |
Questionnaire regarding asthma | V | V | V | V | V |
Questionnaire regarding environment | V | V | V | V | V |
ACT/C-ACT | V | V | V | V | V |
Individual case record | V | V | V | V | V |
WBC, CRP, Eosinophil count, Total IgE | V | Â | V | Â | V |
Skin prick tests | V | Â | V | Â | V |
FEV1, FVC, MMEF (pre- and post-BD) | V | Â | V | Â | V |
Methacholine PC20 or Mannitol PD15 | V | Â | V | Â | V |
FeNO | V | Â | V | Â | V |
Blood sample 15 cc for biomarker study | V |  | V |  | V |
Mobile App for the subgroup | App installation and usage instruction | Confirmation of input and instruction |