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Table 3 Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) at CRP threshold value and in combination with clinical symptoms to differentiate definite bacterial pneumonia from presumed viral and other pneumonias

From: Combination of clinical symptoms and blood biomarkers can improve discrimination between bacterial or viral community-acquired pneumonia in children

  Definite bacterial versus presumed viral pneumonia Definite bacterial versus presumed viral plus other pneumonias
CRP cut-off level (mg/L) Sensitivity Specificity PPV NPV Sensitivity Specificity PPV NPV
≥  72 alone 75 84 53 93 75 82 38 96
≥ 72 and fever 73 90 63 93 73 89 48 96
≥ 72 and absence of rhinorrhoea 65 98 87 93 65 93 59 96
≥ 72 and absence of tachypnoea 65 90 54 93 65 89 38 96