Combination of clinical symptoms and blood biomarkers can improve discrimination between bacterial or viral community-acquired pneumonia in children

Table 3 Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) at CRP threshold value and in combination with clinical symptoms to differentiate definite bacterial pneumonia from presumed viral and other pneumonias

	Definite bacterial versus presumed viral pneumonia				Definite bacterial versus presumed viral plus other pneumonias
CRP cut-off level (mg/L)	Sensitivity	Specificity	PPV	NPV	Sensitivity	Specificity	PPV	NPV
≥ 72 alone	75	84	53	93	75	82	38	96
≥ 72 and fever	73	90	63	93	73	89	48	96
≥ 72 and absence of rhinorrhoea	65	98	87	93	65	93	59	96
≥ 72 and absence of tachypnoea	65	90	54	93	65	89	38	96

ISSN: 1471-2466