From: The impact of emphysema on surgical outcomes of early-stage lung cancer: a retrospective study
Variablea | Non-emphysema (n = 301) | Emphysema (n = 63) | P |
---|---|---|---|
Sex | |||
 Male | 169 (56.1) | 54 (85.7) | < 0.001 |
 Female | 132 (43.9) | 9 (14.3) |  |
Age (y) | 69.0 ± 8.2 | 71.2 ± 8.0 | 0.049 |
BMI (kg/m2) | 22.3 ± 2.9 | 21.2 ± 2.9 | 0.006 |
Smoking index | 565.4 ± 650.4 | 1305.4 ± 719.1 | < 0.001 |
VC (%) | 105.0 ± 62.0 | 101.7 ± 18.1 | 0.633 |
FEV1/FVC (%) | 76.2 ± 8.6 | 67.6 ± 12.9 | < 0.001 |
COPD |  |  | < 0.001 |
 No | 243 (80.7) | 27 (42.9) |  |
 Yes | 58 (19.3) | 36 (57.1) |  |
Surgical procedure | Â | Â | 0.798 |
 Sublobar resection | 119 (39.5) | 26 (41.3) |  |
 Lobectomy | 182 (60.5) | 37 (58.7) |  |
Tumor size (mm) | 22.6 ± 9.8 | 25.9 ± 11.5 | 0.038 |
Histology |  |  | < 0.001 |
 Adenocarcinoma | 250 (83.0) | 33 (52.4) |  |
 Squamous cell carcinoma | 37 (12.3) | 26 (41.3) |  |
 Other | 14 (4.6) | 4 (6.3) |  |
Histologic grade | Â | Â | 0.001 |
 Well differentiated | 159 (52.8) | 18 (28.6) |  |
 Moderately differentiated | 107 (35.6) | 31 (49.2) |  |
 Poorly differentiated | 35 (11.6) | 14 (22.2) |  |
Pleural invasion |  |  | < 0.001 |
 Absent | 226 (75.1) | 33 (52.4) |  |
 Present | 75 (24.9) | 30 (47.6) |  |