Variables | Total patients (n = 97) |
---|---|
Age, years | 67.2 (64.3–70.1) |
Sex, Male, N(%) | 63 (64.3%) |
BMI, kg/m2 | 22.5 (21.7–23.4) |
Underlying lung disease, N(%) | |
Lung cancer | 17 (17.4%) |
Chronic obstructive lung disease | 7 (7.1%) |
Idiopathic pulmonary fibrosis | 7 (7.1%) |
Tuberculosis-destroyed lung | 4 (4.1%) |
Metastatic cancer to lung | 5 (5.1%) |
Others | 15 (15.3%) |
Comorbidities, N(%) | |
Hypertension | 39 (39.8%) |
Diabetes mellitus | 25 (25.5%) |
Cardiovascular disease | 32 (32.7%) |
Cerebrovascular disease | 10 (10.2%) |
Malignancy | 51 (52.0%) |
Liver cirrhosis | 9 (9.2%) |
Chronic kidney disease | 18 (18.4%) |
Intubation, N(%) | 91 (92.9%) |
Indication for intubation, N(%) | |
Type 1 respiratory failure | 83 (84.7%) |
Type 2 respiratory failure | 8 (8.2%) |
Cause of ARDS, N(%) | |
Direct lung injury | 86 (87.8%) |
Indirect lung injury | 11 (12.2%) |
Severity of ARDS | |
Mild | 3 (3.1%) |
Moderate | 29 (29.6%) |
Severe | 65 (67.3%) |
APACHE II score | 23.9 (21.7–26.1) |
SOFA score | 9.2 (8.2–10.3) |
SAPS II score | 37.8 (33.6–42.1) |
Mechanical ventilation settingb | |
PaO2/FiO2 ratio | 82 (64–114) |
Peak inspiratory pressure, cmH20 | 25 (21–29) |
Tidal volume, mL | 440 (398–542) |
Minute volume, L | 10.0 (9.0–12.0) |
Positive end-expiratory pressure, cmH20 | 7 (5–10) |
Serum Activin-A concentration (pg/mL) | 1525.62 (472.60–2578.64) |
Serum Activin-A concentrationa | 2.89 (2.82–2.96) |