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Table 1 Baseline demographics and clinical features of ARDS patients

From: Diagnostic and prognostic values of serum activin-a levels in patients with acute respiratory distress syndrome

Variables

Total patients (n = 97)

Age, years

67.2 (64.3–70.1)

Sex, Male, N(%)

63 (64.3%)

BMI, kg/m2

22.5 (21.7–23.4)

Underlying lung disease, N(%)

 Lung cancer

17 (17.4%)

 Chronic obstructive lung disease

7 (7.1%)

 Idiopathic pulmonary fibrosis

7 (7.1%)

 Tuberculosis-destroyed lung

4 (4.1%)

 Metastatic cancer to lung

5 (5.1%)

 Others

15 (15.3%)

Comorbidities, N(%)

 Hypertension

39 (39.8%)

 Diabetes mellitus

25 (25.5%)

 Cardiovascular disease

32 (32.7%)

 Cerebrovascular disease

10 (10.2%)

 Malignancy

51 (52.0%)

 Liver cirrhosis

9 (9.2%)

 Chronic kidney disease

18 (18.4%)

Intubation, N(%)

91 (92.9%)

Indication for intubation, N(%)

 Type 1 respiratory failure

83 (84.7%)

 Type 2 respiratory failure

8 (8.2%)

Cause of ARDS, N(%)

 Direct lung injury

86 (87.8%)

 Indirect lung injury

11 (12.2%)

Severity of ARDS

 Mild

3 (3.1%)

 Moderate

29 (29.6%)

 Severe

65 (67.3%)

APACHE II score

23.9 (21.7–26.1)

SOFA score

9.2 (8.2–10.3)

SAPS II score

37.8 (33.6–42.1)

Mechanical ventilation settingb

 PaO2/FiO2 ratio

82 (64–114)

 Peak inspiratory pressure, cmH20

25 (21–29)

 Tidal volume, mL

440 (398–542)

 Minute volume, L

10.0 (9.0–12.0)

 Positive end-expiratory pressure, cmH20

7 (5–10)

Serum Activin-A concentration (pg/mL)

1525.62 (472.60–2578.64)

Serum Activin-A concentrationa

2.89 (2.82–2.96)

  1. Abbreviations: BMI body mass index, ARDS acute respiratory distress syndrome, APACHE acute physiologic and chronic health evaluation, SOFA sepsis-related organ failure, SAPS simplified acute physiologic score, LIPS lung injury prediction score, FiO2 fraction of inspired oxygen, PaO2 partial pressure arterial oxygen
  2. alog transformation of levels of serum activin-A was done
  3. bvalues are presented as median(interquartile range)