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Table 2 Primary endpoints assessed at low altitude (760 m)

From: Asthma rehabilitation at high vs. low altitude: randomized parallel-group trial

 

Low altitude rehabilitation group

High altitude rehabilitation group

Between group difference of changes from BL to 3 weeks

Between group difference of changes from BL to 3 months

Baseline

End of rehabilitation (3 weeks)

Follow-up (3 months)

Baseline

End of rehabilitation (3 weeks)

Follow-up (3 months)

PEF-Var.

19 (14;33)

15 (8;23)

15 (9;24)

17 (12;32)

6 (4;9)#

8 (5;14)#

  

change

 

−7.4 (−13.9 to 0)*

−2.5 (-17.5 to 2.1)

 

−10.4 (−21.3 to −3.4)**

−8.9 (-10.3 to -2.8)**

− 5.8 (− 14 to 2)

− 5 (− 13.6 to 5.0)

ACQ

2.7 (1.7;3.2)

0.8 (0.4;1.6)

1.4 (0.9;2.1)

2.0 (1.6;3.0)

0.9 (0.4;1.6)

1.6 (0.9;3.0)

  

change

 

-1.4 (-2.2 to −0.9)***

− 0.9 (− 1.3 to −0.3)**

 

−1.1 (−1.3 to − 0.7)***

−0.2 (-0.9 to 0.4)

0.3 (-0.4 to 1.1)

0.4 (− 0.4 to 1.1)

  1. Note: Data are given as median (quartiles) and median difference (confidence interval)
  2. Abbreviations: PEF-Var. Peak-flow variability, %, ACQ Asthma Control questionnaire. *: p < 0.05; **: p < 0.01; ***: p < 0.001 tested with Wilcoxon test for paired samples (baseline vs. 3 weeks follow up and baseline vs. 3 months follow up). #: p < 0.05 vs. low altitude group