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Table 1 Baseline characteristics of all randomised patients for REMoxTB according to HIV status. The column percentages included in cells indicate the proportion of total n in for HIV-positive and HIV-negative patients belonging to categories of baseline characteristic. Chi square p values comparing the proportions of patients with each characteristic according to HIV status are also provided. *Median time to MGIT culture positive result for all patients = 118 h

From: Toxicity related to standard TB therapy for pulmonary tuberculosis and treatment outcomes in the REMoxTB study according to HIV status

n

HIV-positive

HIV-negative

P value

140

1790

–

Gender

 Male

78 (55.7%)

1267 (70.8%)

< 0.001

 Female

62 (44.3%)

523 (29.2%)

Age in Years

 < 25

20 (14.3%)

545 (30.5%)

< 0.001

 25–35

60 (42.9%)

546 (30.5%)

 > 35

60 (42.9%)

699 (39.0%)

Baseline Weight

 < 40

4 (2.9%)

17 (9.6%)

< 0.001

 40–45

15 (10.7%)

311 (17.4%)

 > 45–55

50 (35.7%)

716 (40.0%)

 > 55–75

65 (46.4%)

552 (30.8%)

 > 75

6 (4.3%)

40 (2.2%)

Ethnicity

 Black

128 (92.1%)

734 (41.0%)

< 0.001

 Asian

3 (2.2%)

587 (32.8%)

 Caucasian

0 (0.0%)

3 (0.2%)

 Other

8 (5.8%)

8 (5.8%)

Smoking Status

 Never

70 (50.0%)

800 (44.7%)

0.141

 Previous

38 (27.1%)

438 (24.5%)

 Current

32 (22.9%)

552 (30.8%)

Chest X-ray

 Cavities

80 (57.1%)

1247 (69.7%)

0.015

 No cavities

37 (26.4%)

349 (19.5%)

MGIT TTP*

 ≥ Median

67 (47.9%)

949 (53.0%)

0.239

 < Median

73 (52.1%)

841 (47.0%)