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Table 2 Overexpression of C/EBPα promotes cell proliferation after exposure to hyperoxia

From: Effects of C/EBPα overexpression on alveolar epithelial type II cell proliferation, apoptosis and surfactant protein-C expression after exposure to hyperoxia

Group

OD value

Air (AG)

1.91 ± 0.63

Air+pcDNA3.1(+)-C/EBPα (A + C)

1.89 ± 0.52&

Air+ pcDNA3.1(+)-empty (A + E)

1.87 ± 0.46

Hyperoxia (HG)

0.89 ± 0.44*

Hyperoxia+pcDNA3.1(+)- C/EBPα (H + C)

2.43 ± 0.25#

Hyperoxia+pcDNA3.1(+)-empty (H + E)

0.76 ± 0.32*

  1. Cell proliferation was analyzed using CCK-8 assay following transfection of C/EBPα after 48 h. Values are means ± SD from ten independent experiments (n = 10); *P < 0.05 vs. AG; #P < 0.05 vs. HG or H + E; &P > 0.05 vs. AG or A + E
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BMC Pulmonary Medicine

ISSN: 1471-2466

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