Total severity of emphysema | Local severity of emphysema | Presence of COPD | Staging of GOLD | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Classify of expression | none-mild | moderate-severe | P value | none | present | P value | No COPD | COPD | P value | GOLD1 | GOLD2,3 | P value |
PD-L1 | ||||||||||||
TC0 | 6 | 1 | 0.28 | 5 | 2 | 0.06 | 3 | 4 | 0.72 | 5 | 2 | 0.61 |
TC1,2,3 | 34 | 18 | 18 | 34 | 26 | 26 | 32 | 20 | ||||
TC0,1 | 14 | 5 | 0.5 | 9 | 10 | 0.36 | 7 | 12 | 0.19 | 11 | 8 | 0.6 |
TC2,3 | 26 | 14 | 14 | 26 | 22 | 18 | 26 | 14 | ||||
TC0,1,2 | 20 | 16 | 0.012 | 13 | 23 | 0.57 | 17 | 19 | 0.71 | 22 | 14 | 0.75 |
TC3 | 20 | 3 | 10 | 13 | 12 | 11 | 15 | 8 | ||||
IC0 | 1 | 0 | 0.49 | 1 | 0 | 0.2 | 0 | 1 | 0.32 | 1 | 0 | 0.44 |
IC1,2,3 | 39 | 19 | 22 | 36 | 29 | 29 | 36 | 22 | ||||
IC0,1 | 2 | 0 | 0.32 | 2 | 0 | 0.07 | 0 | 2 | 0.16 | 2 | 0 | 0.27 |
IC2,3 | 38 | 19 | 21 | 36 | 29 | 28 | 35 | 22 | ||||
IC0,1,2 | 20 | 7 | 0.34 | 14 | 13 | 0.06 | 16 | 11 | 0.15 | 18 | 9 | 0.56 |
IC3 | 20 | 12 | 9 | 23 | 13 | 19 | 19 | 13 | ||||
FGFR1 | ||||||||||||
TC0 | 17 | 9 | 0.72 | 8 | 18 | 0.25 | 13 | 13 | 0.91 | 14 | 12 | 0.21 |
TC1,2,3 | 23 | 10 | 15 | 18 | 16 | 17 | 23 | 10 | ||||
PIK3CA | ||||||||||||
TC0 | 36 | 19 | 0.15 | 22 | 33 | 0.55 | 28 | 27 | 0.32 | 33 | 22 | 0.11 |
TC1,2,3 | 4 | 0 | 1 | 3 | 1 | 3 | 4 | 0 | ||||
PTEN | ||||||||||||
TC0 | 23 | 12 | 0.68 | 17 | 18 | 0.07 | 16 | 19 | 0.52 | 20 | 15 | 0.29 |
TC1,2,3 | 17 | 7 | 6 | 18 | 13 | 11 | 17 | 7 | ||||
p16 | ||||||||||||
TC0 | 13 | 9 | 0.27 | 10 | 12 | 0.43 | 14 | 8 | 0.09 | 12 | 10 | 0.32 |
TC1,2,3 | 27 | 10 | 13 | 24 | 15 | 22 | 25 | 12 |