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Table 1 Characteristics of patients with interstitial lung disease with or without honeycombing

From: The acoustic characteristics of fine crackles predict honeycombing on high-resolution computed tomography

 

Honeycombing group

Non-honeycombing group

P

(n = 24)

(n = 47)

Age (y)

77.0 [69.0–79.0]

67.5 [58.2–74.5]

0.116

Male (%)

13 (54.2)

31 (65.9)

0.336

Body mass index (kg/m2)

23.1 [21.1–24.9]

25.1 [21.4–28.5]

0.951

Radiological findings

 Traction bronchiectasis

15

27

0.684

 Reticulation

18

34

0.812

 Ground-glass opacity

12

42

< 0.001

Lung function

 %VC

77.5 [65.2–93.7]

74.8 [65.5–85.2]

0.728

 %DLCO

62.0 [43.0–70.8]

52.6 [40.9–65.6]

0.258

 Oxygen therapy (%)

6 (25.0)

8 (17.0)

0.427

Laboratory data

 PaO2 (torr)

83.1 [73.2–85.7]

75.2 [72.4–90.2]

0.781

 KL-6 (U/mL)

1509 [780–2385]

1286 [638–2484]

0.149

 SpD (ng/mL)

147.0 [85.7–321.0]

271.0[104.8–361.8]

0.931

 SpA (ng/mL)

70.4 [47.7–121.5]

81.7 [51.0–103.8]

0.185

  1. Data are presented as the median [25th–75th percentile] or as the number of events (percentage). VC Vital capacity, DLCO Diffusing capacity of the lungs for carbon monoxide, PaO2 Partial pressure of arterial oxygen, KL-6 Krebs von der Lungen-6, SpD Surfactant protein D, SpA Surfactant protein A