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Table 2 Comparison of the fine crackle characteristics in the honeycombing and the non-honeycombing groups

From: The acoustic characteristics of fine crackles predict honeycombing on high-resolution computed tomography

 

Honeycombing

Non-honeycombing

P

(n = 24)

(n = 47)

Onset timing

 Early / Mid / Late

20 / 4 / 0

12 / 27 / 8

< 0.001

Number of crackles

 Total (inspiratory phase)

21.5 [14.7–30.3]

8.0 [3.3–13.7]

< 0.001

 Early onset timing

23.8 [16.1–30.8]

17.5 [11.8–20.0]

0.026

 Mid onset timing

12.8 [8.5–16.3]

6.3 [3.0–9.7]

0.099

 Late onset timing

–

3.0 [2.0–7.0]

–

Frequency (Hz)

 F99

841 [782–870]

689 [674–821]

0.001

 F95

527 [442–679]

411 [362–457]

0.003

 F50

259 [233–289]

237 [220–267]

0.052

Waveform (ms)

 2CD

5.5 [5.4–6.4]

7.0 [5.5–7.8]

0.046

 IDW

1.1 [1.0–1.5]

1.5 [1.0–1.5]

0.362

 LDW

1.8 [1.5–2.0]

2.0 [2.0–2.5]

0.004

Amplitude

 A2/A1

0.75 [0.68–0.81]

0.75 [0.62–0.84]

0.553

 A3/A1

0.30 [0.22–0.38]

0.27 [0.20–0.41]

0.344

  1. Data are presented as the median [25th–75th percentile] or as the number of events. F50, F95, and F99 Frequency at 50, 95, and 99% of the total signal power, 2CD Two-cycle duration, IDW Initial deflection width, LDW Largest deflection width