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Table 2 Comparison of the fine crackle characteristics in the honeycombing and the non-honeycombing groups

From: The acoustic characteristics of fine crackles predict honeycombing on high-resolution computed tomography

  Honeycombing Non-honeycombing P
(n = 24) (n = 47)
Onset timing
 Early / Mid / Late 20 / 4 / 0 12 / 27 / 8 < 0.001
Number of crackles
 Total (inspiratory phase) 21.5 [14.7–30.3] 8.0 [3.3–13.7] < 0.001
 Early onset timing 23.8 [16.1–30.8] 17.5 [11.8–20.0] 0.026
 Mid onset timing 12.8 [8.5–16.3] 6.3 [3.0–9.7] 0.099
 Late onset timing 3.0 [2.0–7.0]
Frequency (Hz)
 F99 841 [782–870] 689 [674–821] 0.001
 F95 527 [442–679] 411 [362–457] 0.003
 F50 259 [233–289] 237 [220–267] 0.052
Waveform (ms)
 2CD 5.5 [5.4–6.4] 7.0 [5.5–7.8] 0.046
 IDW 1.1 [1.0–1.5] 1.5 [1.0–1.5] 0.362
 LDW 1.8 [1.5–2.0] 2.0 [2.0–2.5] 0.004
Amplitude
 A2/A1 0.75 [0.68–0.81] 0.75 [0.62–0.84] 0.553
 A3/A1 0.30 [0.22–0.38] 0.27 [0.20–0.41] 0.344
  1. Data are presented as the median [25th–75th percentile] or as the number of events. F50, F95, and F99 Frequency at 50, 95, and 99% of the total signal power, 2CD Two-cycle duration, IDW Initial deflection width, LDW Largest deflection width