Fig. 1

DNA-PKcs expression is reduced in IPF lung tissues. a-d Shown are representative images of normal (a) and IPF (b-d) lung explants from patients with stable (b), rapid (c), and unknown (d) progression of disease stained with anti-DNA-PKcs antibodies or IgG control (inlay) antibodies. e Integrated Optical Density (IOD) of DNA-PKcs IHC staining was quantified using Image-Pro Premier. Groups and scale bars are as indicated on the images. n = 3 normal, n = 3 Stable IPF, n = 3 Rapid IPF, and n = 3 Unknown IPF. *p ≤ 0.05, **p ≤ 0.01, and ***p ≤ 0.005 compared to normal lung explants. One-way ANOVA followed by Tukey