Table 1 Characteristics of healthy controls and FILD cases
Variables | Controls (n = 30) | FILD (n = 30) | p |
|---|---|---|---|
Age (years) | 47 ± 16 | 49 ± 17 | 0.62 |
Male (%) | 12 (40) | 18 (60) | 0.19 |
Body mass index (kg/m2) | 27 ± 9 | 26 ± 4 | 0.47 |
Smoking status | Â | Â | 0.24 |
 Never (%) | 23 (76.6) | 24 (80) |  |
 Past (%) | 7 (23.4) | 4 (13.3) |  |
 Current (%) | 0 | 2 (6.7) |  |
FVC (% predicted) | 93 ± 13 | 58 ± 16 | < 0.01 |
FEV1 (%predicted) | 92 ± 12 | 62 ± 17 | < 0.01 |
FEV1/FVC ratio | 1.07 ± 0.20 | 0.86 ± 0.06 | <  0.01 |
TLC (%predicted) | – | 64 ± 14 |  |
DLCO (%predicted) | – | 43 ± 15 |  |
ILD diagnoses | |||
 FHP |  | 11 |  |
 ILD associated with CTD |  | 7 |  |
 Non-classified IIP |  | 5 |  |
 Idiopathic NSIP - fibrosing pattern |  | 4 |  |
 IPF |  | 2 |  |
 Sarcoidosis with fibrotic pattern |  | 1 |  |
Corticosteroid use | – |  |  |
 Never, n (%) | – | 17 (56.6) |  |
 Current, Prednisone < 20 mg/d n (%) | – | 8 (26.6) |  |
 Current, Prednisone ≥ 20 mg/d | – | 5 (16.6) |  |
Resting dyspnea (MRC) (%) | |||
 1 | – | 5 (16.7) |  |
 2 | – | 11 (36.7) |  |
 3 | – | 9 (30.0) |  |
 4 | – | 4 (13.3) |  |
 5 | – | 1 (3.3) |  |
MIP (cmH20) | 95 ± 34 | 97 ± 34 | 0.86 |
MIP (%predicted) | 89 ± 22 | 81 ± 24 | 0.20 |
MEP (cmH20) | 98 ± 32 | 94 ± 36 | 0.58 |
MEP (%predicted) | 93 ± 32 | 87 ± 28 | 0.44 |
SNIP (cmH20) | 91 ± 23 | 92 ± 23 | 0.82 |
SNIP (%predicted) | 81 ± 20 | 85 ± 24 | 0.45 |