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Table 2 Subject demographic, clinical characteristics, and clinical outcomes by severity of community-acquired pneumonia (CAP)

From: Severe community-acquired pneumonia in general medical wards: outcomes and impact of initial antibiotic selection

 

Severe CAP

(n = 50)

Non-severe CAP

(n = 44)

p-value

Age, y

70.9 ± 14.8

68.2 ± 20.3

.46

Gender (Female)

18 (36)

19 (43.2)

.48

Mechanical ventilation

36 (72)

0

<.001*

Minor criteria ≥3a

14 (28)

0

<.001*

Comorbid conditions:

 None / Single / Multiple

9 (18) / 21 (42) / 20 (40)

17 (38.6) / 17 (38.6) / 10 (22.7)

.05*

 Prior antibiotic therapyb

21 (42)

22 (50)

.44

 ECOG scale ≥2c

32 (64)

22 (50)

.17

 Enteral tube feeding

6 (12)

3 (6.8)

.49

 HCAPd

18 (36)

12 (27.3)

.36

 Pleural effusion

3 (6)

8 (18.2)

.07

 Albumin, g/dL

2.8 ± 0.6

3.1 ± 0.5

.01*

 Globulin, g/dL

3.7 ± 0.8

4.1 ± 0.6

.001*

 Treatment failure

23 (46)

4 (9.1)

<.001*

 Death

14 (28)

4 (9.1)

.02*

 Unfavorable outcomee

25 (50)

6 (13.6)

<.001*

 Length of stay in hospital, df

15.5 ± 12.8

8.3 ± 4.6

.003*

 Hospital-free day, d g

11.6 ± 9.9

19.7 ± 7.7

<.001*

  1. Data are presented as mean ± SD or n (%), unless otherwise stated. aIDSA/ATS 2007 minor criteria7. bPrior antibiotic therapy: systemic antibiotic use in the 90 days prior to this admission. cECOG scale: Eastern Cooperative Oncology Group scale of performance status. dHCAP: Healthcare–associated pneumonia. eUnfavorable outcome includes treatment failure or death during hospital admission. f Length of stay in hospital in patients who survived to hospital discharge. gNumber of days from admission to day 30 that the patient was not admitted to the hospital. *Statistically significant difference
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BMC Pulmonary Medicine

ISSN: 1471-2466

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