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Table 6 Clinical characteristics and clinical outcomes of all patients hospitalized with community-acquired pneumonia (CAP) and patients with severe CAP

From: Severe community-acquired pneumonia in general medical wards: outcomes and impact of initial antibiotic selection

 

All Patients

Severe CAP

Favorable Outcome†

(n = 63)

Unfavorable Outcome†

(n = 31)

p-value

Favorable Outcome†

(n = 25)

Unfavorable Outcome†

(n = 25)

p-value

Age, y

65.6 ± 18.5

77.9 ± 11.8

<.001*

65.5 ± 15.7

76.4 ± 11.7

.008*

Gender (Female)

25 (39.7)

12 (38.7)

.93

9 (36)

9 (36)

1

Comorbid conditions:

  

.04*

  

.65

None

22 (34.9)

4 (12.9)

 

6 (24)

3 (12)

Single

25 (39.7)

13 (41.9)

 

10 (40)

11 (44)

Multiple

16 (25.4)

14 (45.2)

 

9 (36)

11 (44)

Prior antibiotic therapya

29 (46)

14 (45.2)

.94

10 (40)

11 (44)

.77

ECOG ≥2b

31 (49.2)

23 (74.2)

.02*

11 (44)

7 (28)

.24

Enteral tube feeding

5 (7.9)

4 (12.9)

.47

3 (12)

3 (12)

1

HCAPc

20 (31.7)

10 (32.3)

.96

11 (44)

7 (28)

.24

Pleural effusion

7 (11.1)

4 (12.9)

1

0

3 (12)

.23

Albumin, g/dL

3 ± 0.5

2.9 ± 0.6

.24

2.9 ± 0.5

2.8 ± 0.7

.84

Globulin, g/dL

3.9 ± 0.6

3.7 ± 0.9

.26

3.7 ± 0.6

3.6 ± 1

.79

  1. Data are presented as mean ± SD or n (%), unless otherwise stated. †Unfavorable outcome includes treatment failure or death during hospital admission. aPrior antibiotic therapy: systemic antibiotic use in the 90 days prior to this admission. bECOG scale: Eastern Cooperative Oncology Group scale of performance status
  2. cHCAP: healthcare–associated pneumonia. *Statistically significant difference