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Table 8 Risk factors of unfavorable outcome† in patients hospitalized with community-acquired pneumonia (CAP) by univariate and multivariate analyses

From: Severe community-acquired pneumonia in general medical wards: outcomes and impact of initial antibiotic selection

 

Univariate analysis

Multivariate analysis

p-value

p-value

OR (95%CI)

ALL hospitalized patients with CAP (n = 94)

 Age

<.001*

.002*

1.07 (1.03–1.1)

 Comorbid conditions

.04*

NS

 

 ECOG ≥2a

.02*

NS

 

 Severe CAP

<.001*

.001*

7.9 (2.4–26.3)

 Guideline-discordant treatmentb

.01*

.079

2.5 (0.9–7.1)

Hospitalized patients with severe CAP (n = 50)

 Age

.008*

.01*

1.1 (1.01–1.1)

 Comorbid conditions

.65

NS

 

 ECOG ≥2a

.24

NS

 

 Guideline-discordant treatmentb

.02*

.02*

4.6 (1.3–17.1)

  1. OR: odds ratio. CI: confidence interval
  2. †Unfavorable outcome includes treatment failure or death during hospital admission
  3. aECOG scale: Eastern Cooperative Oncology Group scale of performance status
  4. bThe 2007 ATS/IDSA guidelines on the management of community-acquired pneumonia in adults7
  5. *Statistically significant difference. NS: not significant difference