Table 1 Clinical characteristics and final diagnosis of the study population
Characteristics | Biopsy-first group | Brushing-first group | P value |
|---|---|---|---|
N = 219 | N = 219 | ||
Age, years | 66 ± 13 | 65 ± 11 | 0.344 |
≥ 65 | 123 (56) | 119 (54) | 0.701 |
Gender | |||
Male | 120 (55) | 119 (54) | 0.924 |
Lobar location | |||
Right upper lobe | 63 (29) | 52 (24) | 0.547 |
Right middle lobe | 18 (8.2) | 13 (5.9) | |
Right lower lobe | 42 (19) | 49 (22) | |
Left upper lobe | 56 (26) | 65 (30) | |
Left lower lobe | 40 (18) | 40 (18) | |
Lesion size, mm | 36 ± 16 | 37 ± 17 | 0.734 |
≤ 20 | 22 (10) | 29 (13) | 0.297 |
> 20 | 197 (90) | 190 (87) | |
CT appearance | |||
Solid | 197 (90) | 192 (88) | 0.448 |
Non-solid | 22 (10) | 27 (12) | |
CT bronchus sign | |||
Presence | 215 (98) | 216 (99) | 0.999 |
Absence | 4 (1.8) | 3 (1.4) | |
Probe location | |||
Within | 177 (81) | 198 (90) | 0.004 |
Adjacent to or outside | 42 (19) | 21 (9.6) | |
Lesion pathology | |||
Adenocarcinoma | 162 (74) | 150 (69) | 0.656 |
Squamous cell carcinoma | 18 (8.2) | 18 (8.2) | |
Small cell carcinoma | 7 (3.2) | 8 (3.7) | |
Non-small cell carcinoma | 22 (10) | 27 (12) | |
Metastasis | 5 (2.3) | 11 (5.0) | |
Others | 5 (2.3) | 5 (2.3) | |
Diagnostic yield | 158 (72) | 162 (74) | 0.667 |