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Table 1 Baseline characteristics in the full cohort and stratified by ILD diagnosisa

From: Baseline characteristics and comorbidities in the CAnadian REgistry for Pulmonary Fibrosis

CharacteristicFull cohort
n = 1285
IPF
n = 317
Non-IPF IIP
n = 39
HP
n = 97
Sarcoid
n = 41
CTD-ILD
n = 428
Unclassifiable
n = 286
Other ILD
n = 77
Age, years64.8+/− 11.870.9+/−8.561.7+/− 11.263.7+/− 10.255.6+/− 11.560.3+/− 11.967.6+/− 10.562.0+/− 14.7
Male sex633 (49.3)229 (72.2)19 (48.7)43 (44.3)21 (51.2)130 (30.4)150 (52.5)41 (53.3)
Ever smoked781 (62.9)240 (78.2)29 (76.3)55 (57.9)19 (47.5)221 (53.8%)177 (64.4)40 (52.6)
Pack-years20.5 (8.3, 36.0)25.0 (14.3,40.0)21.3 (11.1, 31.0)16.1 (7.0, 35.1)7.0 (2.7, 11.4)15.0 (4.7, 30.0)22.0 (10, 37.5)27.1 (5.3, 52.5)
BMI, kg/m228.7+/−5.828.7+/−4.929.3+/−6.530.5+/−6.229.0+/− 6.327.1+/− 5.730.3+/− 5.828.9+/− 6.4
FVC, %-predicted74.5+/−20.372.8+/− 19.572.1+/− 18.367.7+/− 21.086.9+/−16.074.5+/−19.976.0+/− 20.779.9+/−22.9
DLCO, %-predicted56.7+/−20.149.9+/−16.752.4+/−20.454.0+/−19.080.1+/− 18.456.4+/− 19.259.2+/− 19.568.7+/−25.7
Oxygen use259 (22.1)100 (34.1)11 (29.0)27 (31.0)2 (5.3)59 (15.3)45 (17.4)15 (21.1)
SLB270 (21.0)48 (15.1)23 (59.0)50 (51.6)16 (39.0)52 (12.2)65 (22.7)16 (20.8)
CCI1.7+/−1.31.3+/−1.21.2+/− 0.91.3+/− 1.01.4+/− 1.42.1+/− 1.01.7+/− 1.61.7+/−1.4
  1. Other ILD includes: Vasculitis, diffuse alveolar hemorrhage, drug related, pneumoconiosis, post-acute respiratory disease syndrome, aspiration, eosinophilic pneumonia, pleuroparenchymal fibroelastosis, lymphangioleiomyomatosis, Langehan’s cell histiocytosis, neuroendocrine cell hyperplasia, pulmonary alveolar proteinosis
  2. Abbreviations: BMI Body mass index, CCI Charlson Comorbidity Index, CTD-ILD Connective tissue disease-associated ILD, DLCO Diffusing capacity of the lung for carbon monoxide, FVC Forced vital capacity, HP Hypersensitivity pneumonitis, IIP Idiopathic interstitial pneumonia, ILD Interstitial lung disease, IPF Idiopathic pulmonary fibrosis, SLB Surgical lung biopsy
  3. a Data shown are mean+/−standard deviation, median (interquartile range) or number (percent)
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