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Table 3 Lung function parameters, 6MWT and K-BILD results divided by smoking status and gender

From: Gender differences at presentation of idiopathic pulmonary fibrosis in Sweden

 TotalNever smokerEx-smoker
MaleFemaleMaleFemaleMaleFemale
Lung function
 FVC% (N = 287)N = 198N = 89N = 50N = 37N = 139N = 47
 68.9 ± 14.4*73.0 ± 17.769.7 ± 18.066.8 ± 16.868.7 ± 12.7**75.8 ± 16.3
 FEV1% (N = 307)N = 215N = 92N = 54N = 38N = 152N = 49
 76.1 ± 16.176.0 ± 17.776.8 ± 18.571.3 ± 18.976.4 ± 14.678.6 ± 16.1
 TLC%, (N = 193)N = 141N = 52N = 35N = 21N = 103N = 31
 62.2 ± 11.8*68.6 ± 11.361.8 ± 11.964.4 ± 10.862.0 ± 11.7***71.3 ± 11.0
 DLCO% (N = 221)N = 158N = 63N = 39N = 25N = 113N = 35
 45.2 ± 13.648.8 ± 14.449.7 ± 14.146.7 ± 14.243.8 ± 13.3*49.3 ± 13.3
6WMT (N = 198)N = 139N = 59N = 35N = 22N = 102N = 35
 6MWD, (M ± SD, m)427 ± 128411 ± 113439 ± 136*355 ± 140426 ± 125446 ± 79
 B-SpO2% (M ± SD, %)95.7 ± 2.3095.9 ± 2.395.4 ± 2.095.8 ± 2.795.8 ± 2.495.9 ± 2.1
 L-SpO2% (M ± SD, %)85.9 ± 6.4486.6 ± 7.485.8 ± 6.588.0 ± 8.585.8 ± 6.485.7 ± 6.6
K-BILD (N = 292)N = 210N = 82N = 55N = 33N = 146N = 44
 Psychological55.1 ± 16.654.9 ± 15.657.8 ± 16.153.0 ± 13.254.4 ± 17.055.6 ± 17.7
 Breathlessness and activities36.8 ± 18.740.0 ± 17.138.5 ± 21.934.5 ± 13.737.2 ± 17.141.3 ± 16.7
 Chest symptoms64.1 ± 21.766.0 ± 22.971.4 ± 21.4*60.6 ± 20.462.5 ± 21.467.9 ± 24.2
 Total53.6 ± 10.954.3 ± 10.155.5 ± 11.151.8 ± 7.853.3 ± 11.055.1 ± 11.3
  1. M mean, SD standard deviation, FVC% forced vital capacity, % of expected, FEV1% forced expiratory volume in first second, % of expected, TLC% total lung capacity, % of expected, DLCO% % diffusing capacity for carbon monoxide, 6MWD 6 min walking distance, B-SpO2% Saturation level for oxygen, at rest, L-SpO2% Saturation level for oxygen, lowest during/after test, K-BILD King’s Brief Interstitial Lung Disease questionnaire
  2. *: p < 0.05, ** p < 0.01, *** p < 0.001 males vs. females