Indwelling pleural catheters for malignancy-associated pleural effusion: report on a single centre’s ten years of experience

Table 4 Univariate and multiple Cox regression analysis for overall survival after IPC placement (OS2)

Variable	Univariate Cox regressionfor OS2 (n = 395 patients)			Multivariate Cox regressionfor OS2 (n = 395 patients)
Variable	HR	95% CI	p-value	HR	95% CI	p-value
Sex
male vs. female	1.143	0.908–1.437	0.254
Age
< 60 vs. ≥60	0.796	0.633–1.000	0.050^a	0.803	0.638–1.009	0.060
< 65 vs. ≥65	0.886	0.712–1.102	0.276
< 70 vs. ≥70	0.858	0.681–1.081	0.194
< 75 vs. ≥75	1.046	0.773–1.415	0.769
Cancer entity
Gynaecologic cancer vs. other	0.753	0.604–0.940	0.012^a	0.787	0.630–0.984	0.036^a
Lung cancer vs. other	1.283	0.997–1.651	0.053
Cause of effusion
MPE vs. other	0.946	0.683–1.310	0.737
MPE vs. paramalignant effusion	0.837	0.535–1.310	0.437
Laterality
Bilateral vs. unilateral	0.702	0.507–0.972	0.033^a	0.703	0.510–0.968	0.031^a
Bilateral vs. unilateral (Ovarian vs. else)	0.671	0.488–0.924	0.015^a
left vs. right	0.982	0.787–1.224	0.870
Pleurodesis
Yes vs. No	1.192	0.854–1.664	0.302
Complications
Yes vs. No	0.869	0.624–1.210	0.406

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