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Table 3 Nosocomial infections according to CDC criteria

From: Anemia and red blood cell transfusion practice in prolonged mechanically ventilated patients admitted to a specialized weaning center: an observational study

 

All patients (n = 378)

Transfused (n = 168)

Non-transfused (n = 210)

P valued

No. of patients with nosocomial infections

158 (41.8)

91 (54.2)

67 (31.9)

<  0.001a

 No. of patients with MDR-NI

24 (15.2)

16 (17.6)

8 (11.9)

n.s.a

No. of nosocomial infections

210

133

77

–

 No. of MDR-NI

28 (13.3)

20 (15.0)

8 (10.4)

n.s.a

 No. of NI per patient

0.56 (± 0.78)

0.79 (± 0.92)

0.37 (± 0.57)

<  0.001c

No. of nosocomial infections by site/type

 Lower respiratory tract infection

72 (19.0)

48 (28.7)

24 (11.4)

<  0.001a

  Ventilator-associated pneumonia

24 (6.4)

22 (13.1)

2 (1.0)

<  0.001a

  Tracheobronchitis

48 (12.7)

26 (15.5)

22 (10.5)

n.s.a

 Urinary tract infection

61 (16.1)

32 (19.0)

29 (13.8)

n.s.a

 Gastroenteritis

32 (8.5)

20 (11.9)

12 (5.7)

n.s.a

  Clostridium-associated infection

29 (7.7)

17 (10.1)

12 (5.7)

 

  Norovirus infection

3 (0.8)

3 (1.8)

0 (0.0)

 

 Decubitus infection

7 (1.9)

5 (3.0)

2 (1.0)

n.s.b

 Catheter-related BSI

22 (5.8)

13 (7.7)

9 (4.3)

n.s.a

 Other

16 (4.2)

15 (8.9)

1 (0.5)

<  0.001b

  Biliary tract infection

1

1

0

 

  Lung abscess and empyema

1

1

0

 

  Endocarditis

1

1

0

 

  Laboratory-confirmed BSI

3

3

0

 

  Mediastinitis

1

1

0

 

  Peritonitis (primary/secondary)

3

3

0

 

  Skin and soft tissue infection

1

1

0

 

  Surgical site infection

5

4

1

 

No. of isolated pathogens

241

153

88

–

 No. of isolated MDR pathogens

30 (12.4)

21 (13.7)

9 (10.2)

n.s.a

Time to 1st nosocomial infection (days)

14.7 (± 11.4)

16.4 (± 12.3)

12.5 (± 9.7)

0.030c

  1. Legend
  2. Results are presented as mean values (± standard deviation), number, or number (%)
  3. a: Chi square test
  4. b: Fisher’s exact test
  5. c: Student’s t-test
  6. d: P value for differences between transfused and non-transfused patients
  7. Abbreviations: No. Number, n.s. not significant (p > 0.05), BSI Bloodstream infection, MDR Multidrug resistant, NI Nosocomial infection