Skip to main content

Table 4 Impact of red blood cell transfusion on outcome parameters: Results of univariate and multivariate analyses

From: Anemia and red blood cell transfusion practice in prolonged mechanically ventilated patients admitted to a specialized weaning center: an observational study

Outcome

Unadjusted OR (95% CI)

P value

Adjusted OR (95% CI)

P value

 Weaning failure (Category 3c)

1.689 (1.085–2.629)

0.020

–

n.s.a

 Hospital mortality

3.168 (1.625–6.177)

0.001

2.050 (0.995–4.224)

0.052a

 Nosocomial infections

2.522 (1.625–6.177)

<  0.001

–

n.s.a

Outcome

Unadjusted β (95% CI)

P value

Adjusted β (95% CI)

P value

 Weaning duration

12.386 (9.335–15.436)

<  0.001

12.386 (9.335–15.436)

<  0.001b

 Hospital length of stay

18.664 (11.464–25.864)

<  0.001

16.116 (8.925–23.306)

< 0.001b

  1. Legend
  2. a: Logistic regression analysis
  3. b: Linear regression analysis
  4. Results were adjusted for baseline demographics and clinical characteristics (age, gender, body mass index, APACHE-II, Albumin, hemoglobin on admission, smoking history), comorbidities (Charlson comorbidity index, COPD, renal insufficiency), causes of acute respiratory failure (acute exacerbation of COPD, cardiopulmonary resuscitation, cardiac failure, surgery) as well as for mean hemoglobin, FFP/platelets, gastrointestinal bleeding, and other bleeding events in the course of weaning. The results for nosocomial infections were adjusted for weaning duration.
  5. Abbreviations: OR Odds ratio, 95% CI 95% confidence interval, n.s. not significant (p > 0.05)