Table 1 Performance of metagenomic next-generation sequencing (mNGS) and conventional testing in diagnosis of mixed pulmonary infection
From: Metagenomic next-generation sequencing for mixed pulmonary infection diagnosis
Diagnostic testing | Sensitivity % (95% CI) | Specifificity % (95% CI) | PPV % (95% CI) | NPV % (95% CI) |
|---|---|---|---|---|
Conventional laboratory-based diagnostic testing | 13.9 (5.2–31.0) | 94. (71.9–99.7) | 83.3 (36.5–99.1) | 36.7 (23.8–51.7) |
mNGS | 97.2 (83.8–99.9) | 63.2 (38.6–82.8) | 83.3 (68.0–92.5) | 92.3 (62.1–99.6) |